Peel and devein the jumbo shrimp, leaving the tails on if desired. Pat them dry.
Season the shrimp with salt, black pepper, and garlic powder.
Coat each shrimp in flour, then dip into beaten egg.
Roll the shrimp in breadcrumbs until completely covered.
Heat oil in a deep skillet or fryer over medium-high heat.
Fry the breaded shrimp for 2–3 minutes on each side until golden brown and crispy.
Remove and place on paper towels to drain excess oil. Serve hot with lemon wedges and dipping sauce.